Syndromes with Craniofacial Abnormalities Codexery

Leontiasis ossea

Rare craniofacial bone overgrowth, a symptom of other diseases.

Leontiasis ossea, also called lion face syndrome, is a rare condition marked by overgrowth of facial and cranial bones. It is not a disease itself but a symptom of other disorders such as Paget's disease, fibrous dysplasia, hyperparathyroidism, and renal osteodystrophy. Progressive enlargement of the maxilla can encroach on the orbit, mouth, nose, and sinuses, leading to exophthalmos, blindness from optic nerve compression, and difficulty breathing or eating. In a less common form, all cranial and facial bones are affected, with gradual loss of senses and death from cerebral pressure. Treatment involves surgical removal of overgrown bone.

Quick Facts

Also known as
  • leontiasis
  • lion face
  • lion face syndrome
Associated diseases
  • Paget's disease
  • fibrous dysplasia
  • hyperparathyroidism
  • renal osteodystrophy
Less common form
  • overgrowth of all cranial and facial bones
  • loss of senses
  • death from cerebral pressure
Treatment
exposing overgrown bone and chipping away pieces or excising entirely

Facts from the source article.

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