Mary E. Brunkow
American molecular biologist who co-identified FOXP3 and won the 2025 Nobel Prize.
Mary Elizabeth Brunkow is an American molecular biologist and immunologist who co-identified the gene FOXP3 as the cause of the scurfy mouse phenotype, a discovery foundational to regulatory T cell biology. In 2025, she shared the Nobel Prize in Physiology or Medicine with Fred Ramsdell and Shimon Sakaguchi for their work on peripheral immune tolerance.
Quick Facts
- Born
- 1961
- Birthplace
- Portland, Oregon, U.S.
- Education
- University of Washington (BS); Princeton University (PhD)
- Known for
- FOXP3
- Fields
- Immunology; Molecular biology
- Workplaces
- Institute for Systems Biology; Celltech R&D
- Thesis year
- 1991
- Doctoral advisor
- Shirley M. Tilghman
Facts from the source article.
Did You Know?
- Brunkow graduated from St. Mary's Academy in Portland in 1979.
- She worked at Celltech R&D in Bothell, Washington, where she and Fred Ramsdell performed their Nobel Prize-winning work on FOXP3.
- She later became senior program manager at the Institute for Systems Biology in Seattle.
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