Actinic prurigo
A rare, chronic, sunlight-induced itchy skin eruption.
Actinic prurigo is a rare skin eruption induced by sunlight, characterized by itchy papules or nodules. It is notable for its chronic and persistent nature, often beginning in childhood, and for its association with the human leukocyte antigen HLA-DR4. Some medical experts consider it a variant of polymorphous light eruption, while others use the term for several distinct photodermatoses.
Quick Facts
- Specialty
- dermatology
Facts from the source article.
Symptoms
The condition presents with itchy, inflamed papules, nodules, and plaques. Lesions usually appear hours or days after UV exposure on sun-exposed areas such as the face, neck, arms, hands, and legs. However, lesions can also occur on covered skin, complicating diagnosis. Symptoms are chronic and typically worsen in spring and summer with increased sunlight.
Treatment
There is no cure; treatment focuses on symptom relief. Options include topical creams like Tacrolimus and Betamethasone, and systemic immunosuppressants such as Prednisone. Thalidomide has proven effective in some cases. Patients are advised to minimize sun exposure and use strong sunscreen year-round, as UVA penetrates clouds. Alternative methods include UV hardening, meditation, cognitive behavioral therapy, and UVA desensitization phototherapy.
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