Familial dysbetalipoproteinemia
A lipid disorder causing xanthomas and early heart disease.
Last updated
Familial dysbetalipoproteinemia, also known as type III hyperlipoproteinemia, is a metabolic disorder marked by elevated total cholesterol and triglycerides with decreased HDL levels. It is notable for causing premature atherosclerosis and early cardiovascular events in young or middle-aged adults.
Quick Facts
- Total cholesterol
- Increased
- Hdl levels
- Decreased
- Skin signs
- Xanthoma striatum palmare, tuberoeruptive xanthomas
- Genetic risk factor
- Mutation in apolipoprotein E (ApoE), especially two copies of ApoE2
Facts from the source article.
More in Skin Conditions Resulting from Errors in Metabolism
Sources
Compiled from Wikipedia and the sources listed below. Text from Wikipedia is available under CC BY-SA 4.0; this entry is adapted from it.
- Wikipedia: Familial dysbetalipoproteinemia (CC BY-SA 4.0).
- Word definitions: the Codexery glossary, each quoted from its Wikipedia article.
Spotted an error? Know more?
Reader corrections go straight into our review queue. Suggest an edit · How this site is sourced
Comments
Loading…