Chicago

The walled-off city of insect spirits.

Jstuby · CC0

Chicago in Shadowrun is the city sealed behind a wall after the Universal Brotherhood's insect-spirit hive there was botched, to keep the rampaging spirits inside. It has served as a setting for organised-play missions as the formerly walled-off wastelands of Chicago.

Quick Facts

Cause: Botched Universal Brotherhood hive
Cleansed with: FAB-3

Reader's Guide

The background of Shadowrun Returns ties the Chicago disaster to the Universal Brotherhood, whose chapters elsewhere hold similar hives, including one in Seattle, and FAB-3 is later used to cleanse Chicago of its insect spirit infestation.