Registry of Toxic Effects of Chemical Substances
Compilation of toxicity data from open scientific literature.
The Registry of Toxic Effects of Chemical Substances is a toxicity database compiled from published scientific literature, without assessing study validity. It was once a free publication by the US National Institute for Occupational Safety and Health, but is now licensed through BIOVIA.
Quick Facts
- Established by
- Section 20(a)(6) of the Occupational Safety and Health Act of 1970 (PL 91-596)
- Original publication date
- June 28, 1971
- Original name
- Toxic Substances List
- Transferred to private company
- December 2001
- Current owner
- Dassault Systèmes (via BIOVIA brand)
Facts from the source article.
Did You Know?
- Six types of toxicity data are included: primary irritation, mutagenic effects, reproductive effects, tumorigenic effects, acute toxicity, and other multiple dose toxicity.
- Specific numeric toxicity values such as LC50, TDLo, and TCLo are noted along with species studied and route of administration.
- The studies in RTECS are not evaluated in any way.
History
The database was mandated by the US Congress under the Occupational Safety and Health Act of 1970. The first edition, called the Toxic Substances List, appeared on June 28, 1971, with data on about 5,000 chemicals. The name later changed to Registry of Toxic Effects of Chemical Substances. In 2000, NIOSH sought proposals to transfer the database to a private company, and in December 2001 it was transferred to MDL, a subsidiary of Elsevier. After several acquisitions, Dassault Systèmes acquired it and now licenses it through BIOVIA. Third-party distributors such as the Canadian Centre for Occupational Health and Safety also sell licenses for English and French versions.
More in Toxic Effects of Substances Chiefly Nonmedicinal As to Source
Spotted an error? Know more?
Reader corrections go straight into our review queue. Suggest an edit · How this site is sourced