Symptoms and Signs: Endocrinology, Nutrition, and Metabolism Codexery

Anorexia (symptom)

Loss of appetite as a symptom, not a diagnosis.

Anorexia, as a symptom, refers to a loss of appetite. It is distinct from anorexia nervosa, which is a mental disorder. Anorexia can arise from numerous medical conditions, psychological factors, or environmental influences, and it is considered a symptom rather than a diagnosis. The term originates from Ancient Greek, meaning 'without appetite.'

field
Medicine
known_for
Loss of appetite as a symptom of various conditions
etymology
Ancient Greek: ανορεξία (ἀν-, 'without' + όρεξις, 'appetite')
common_causes
Over 80 listed, including cancer, depression, diabetes, and side effects of drugs

Quick Facts

Specialty
Gastroenterology, family medicine, internal medicine
Symptoms
Not wanting to eat, no hunger, dizziness, weakness
Causes
Achy stomach, gastroparesis, food poisoning

Facts from the source article.

Lore & Background

Anorexia is a symptom characterized by a decreased or absent desire to eat. It can manifest subtly, such as not feeling hungry, or more noticeably, such as nausea at the thought of food. Clinically significant anorexia leads to weight loss or muscle loss that is not intentional. The symptom occurs in humans and non-human animals, including cats, dogs, cattle, goats, and sheep, where it may be called inappetence.

Reader's Guide

The physiology of anorexia involves complex interactions between peripheral signals (taste, smell, gut hormones) and central neurotransmitters in the hypothalamus, including neuropeptide Y, leptin, ghrelin, insulin, serotonin, and orexins. Imbalances in these signals can cause loss of appetite. Common causes range from infections and chronic diseases to psychological stress and drug side effects. Complications include dehydration, electrolyte imbalances, and sudden cardiac death due to acquired long QT syndrome. Refeeding syndrome is a potentially fatal risk when feeding resumes after prolonged starvation, requiring careful medical supervision. Management may involve orexigenic drugs.

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