Genetics Codexery — Data & Quality

We publish our audit record because accuracy claims should be checkable. Every entry on this site runs through an automated fact-audit pipeline (accuracy audit → source-grounded repair → visual QA); this page is generated from that pipeline's own report, not written by hand.

Last full accuracy audit: 2026-09-08 · 28 entries checked · 10 flagged · 22 issues confirmed · 10 corrected · 12 still open

Recent findings (audit lane, verbatim)

Allele — The entry states that the ABO blood group has six common alleles, but the widely accepted canon is that the ABO blood group is controlled by three main alleles (A, B, and O), not six.

Central dogma of molecular biology — The entry states that Crick's version 'remains valid today' while Watson's version 'does not,' but Crick's original 1958 formulation did not include reverse transcription, so it is not fully valid in the same sense without noting the 1970 clarification.

DNA ligase — The entry states that each phosphodiester bond consumes two ATP molecules and requires AMP; in reality, each ligation event consumes one ATP (or NAD) molecule, and AMP is a transient intermediate, not an additional requirement.

DNA ligase — The reaction is described as having four steps, but the standard mechanism has three steps: adenylylation of the enzyme, transfer of AMP to the 5' phosphate of the donor, and phosphodiester bond formation with release of AMP. The claim of a first step involvin

DNA polymerase — The entry conflates the intrinsic error rate of DNA polymerase alone (around one error per 10^4 to 10^5 base pairs) with the final error rate after proofreading and mismatch repair (about one error per billion base pairs).

DNA polymerase — The entry states that DNA polymerase II was discovered in 1970 by Thomas Kornberg and Malcolm E. Gefter, but the actual first discovery is often attributed to earlier work (e.g., by Knippers, or by Moses and Richardson in 1969).

DNA sequencing — The entry uses 'GenB' instead of the correct name 'GenBank'.

Dominance (genetics) — The statement 'Y-linked traits cannot be dominant or recessive because there is only one Y chromosome' is misleading: Y-linked traits are typically considered dominant in males because there is no homologous allele on the X chromosome to mask them, though the

Enhancer (genetics) — The entry states that enhancers exist in both prokaryotes and eukaryotes, but true enhancers (defined as long-distance, orientation-independent regulatory elements) are not found in prokaryotes.

Enhancer (genetics) — The entry states that the first eukaryotic enhancer was discovered in 1983, but the first eukaryotic enhancer was actually discovered in 1981 in the SV40 virus.

Genetic code — The entry states that the triplet code allows 'a maximum of 64 amino acids', but the correct statement is that it allows a maximum of 64 possible codons, not amino acids.

Genetic code — The entry says George Gamow 'created the RNA Tie Club, as suggested by Watson', but established canon states the club was founded by Gamow himself, with Watson as a member, not that Watson suggested its creation.

Open data

All content is fetchable as JSON at /data/content/ · llms.txt · sitemap

Corrections

Spotted an error? Suggest an edit — reader reports go straight into the audit queue.

← back to Genetics