Escherichia coli NC101
Pro-carcinogenic adherent-invasive E. coli strain promoting mucinous adenocarcinoma.
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Escherichia coli NC101 is a pro-carcinogenic, adherent-invasive strain isolated from a specific pathogen-free wild-type mouse. It is a nicotinic acid auxotroph and pathobiont that promotes mucinous adenocarcinoma in azoxymethane-treated mice by altering microbial composition and expanding genotoxic microorganisms.
Quick Facts
- Serotype
- O2:H6/41
- Isolation location
- North Carolina State University
- Key genetic feature
- Missense mutation in nadA (quinolinate synthase A)
- Associated cancer type
- Mucinous adenocarcinoma
- Experimental model
- Azoxymethane-treated mice
Facts from the source article.
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Sources
Compiled from Wikipedia and the sources listed below. Text from Wikipedia is available under CC BY-SA 4.0; this entry is adapted from it.
- Wikipedia: Escherichia coli NC101 (CC BY-SA 4.0).
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